Catholic Health East is a multi-institutional Catholic health system, which is co-sponsored by 12 religious congregations, and Hope Ministries, a Public Juridic Person within Catholic Health East. Based in Newtown Square, Pennsylvania, the System provides the means to ensure the continuation of the Catholic identity and operational strength of the sponsors' health ministries, which are located within 11 eastern states from Maine to Florida.

The System includes 34 acute care hospitals, 4 long term acute care hospitals, 36 freestanding and hospital-based long term care facilities, 12 assisted living facilities, 5 continuing care retirement communities, 7 behavioral health and rehabilitation facilities, 25 home health/hospice agencies, and numerous ambulatory and community-based health services. Catholic Health East facilities employ approximately 50,000 full-time employees as partners in ministry.